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- W2391800200 abstract "Objective To study the detection of 3 nitrotyrosine(3-NT),glycosylated hemoglobin(HbA1c)and other biochemical indicators in patients with type II diabetes serum and its clinical significance.Method According to case-control study,40 patients with type Ⅱ diabetes were recruited and 20 cases of healthy volunteers were taken as the control case.The selected subjects were examined in anthropometry and blood biochemistry,such as the level of serum 3-NT,and its clinical significance was analyzed.Results 3-NT in the serum,body mass index(BMI),HbA1c,fasting plasma glucose(FPG),triglyceride(TG),creatinine(Cre),systolic blood pressure and diastolic blood pressure in the diabetic group were significantly higher than those in the normal control group(P0.05).Compared with those in the normal control group,various indicators in the simple diabetic group and the group of diabetes with complications,such as 3-NT,BMI,HbA1c,FPG,TG,Cre,systolic blood pressure and diastolic blood pressure were significantly different statistically.The multiple linear stepwise regression analysis on the 3-nitrotyrosine and the other variables in the serum of diabetic patients showed that serum 3-nitrotyrosine content of the diabetic patients was influenced by BMI and CHO.Conclusion Mornitoring 3-NT,HbA1c,BMI and blood lipids and other biochemical indicators in patients with diabetes is very important.The simultaneous detection of 3-NT,HbA1c,BMI and blood lipids is of great significance in clinical diagnosis and treatment of diabetes and its complications." @default.
- W2391800200 created "2016-06-24" @default.
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- W2391800200 date "2012-01-01" @default.
- W2391800200 modified "2023-09-23" @default.
- W2391800200 title "Detection of 3 Nitrotyrosine,Glycosylated Hemoglobin and Other Biochemical Indicators in Serum of Patients with Type II Diabetes and Its Clinical Significance" @default.
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