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- W2391848187 abstract "Objective Neostigmine test is one of the most important methods for diagnosis of myasthenia gravis (MG), up to now quantitative assessment of the results for such test is still not practically available. In this study, it is attempted to set up the quantitative assessment criteria. Methods Neostigmine (1 5 mg, for children, the dose should be decreased according to their age) and atropine (1 0 mg) were intramuscularly administered for 54 cases with clinically confirmed MG and 6 cases with other neurological disorders. Each item was determined quantitatively before and every 10 minutes after intramuscular injection of neostigmine. The data difference of each item between every 10 minute after and before injection of neostigmine were recorded, The mean value of data difference of six times was accepted as the cut off value for each item. Results The measurement of each item strength in the involved muscles proved to be reproducible for inter observer agreement ( K =0 62-0 86). The criteria were highly specific (100%) and sensitive (90 7%). Conclusion The criteria established in this study is reliable, accurate and objective in the assessment of neostigmine test." @default.
- W2391848187 created "2016-06-24" @default.
- W2391848187 creator A5005786604 @default.
- W2391848187 date "2000-01-01" @default.
- W2391848187 modified "2023-09-25" @default.
- W2391848187 title "Assessment Criteria for Neostigmine Test and Its Clinical Application" @default.
- W2391848187 hasPublicationYear "2000" @default.
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