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- W2391929210 abstract "Objective To study the ihibitiory effect of chrysin on the gastric cancer cells(SGC-7901) in vivo and to explore the mechanisms of the effect.Methods 24 molels of human gastric carcinoma xenograft in Balb/c-nude mouse were established to be divided into four groups randomly(6 in each group): control group,30 mg/kg chrysin group,60 mg/kg chrysin group,120 mg/kg chrysin group.The inhibitory effect on tumors in each group was studied.The apoptosis rate and s-phase fraction were analyzed by Flow Cytometry.Results The average weight of tumors in treated groups were significantly less than which in the control group(P0.01),the inhibitory rate was 0%,23.80%,40.36%,61.19% respectively.The apoptosis rate was(7.8±3.7)%,(15.2±2.2)%,(22.0±3.1)%,(53.0±9.2)% respectively,the apoptosis rate of group 60 mg/kg and 120 mg/kg were significantly lower compared with control group(P0.01). Conclusion Chrysin inhibits the growth of SGC-7901 grastic cancer in vivo.The mechanism for the effect might be related to the apoptosis inducement." @default.
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- W2391929210 date "2009-01-01" @default.
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- W2391929210 title "Inhibitory Effect of Chrysin on the Gastric Cancer SGC-7901 Cells in Vivo" @default.
- W2391929210 hasPublicationYear "2009" @default.
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