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- W2391931738 abstract "Objective:To evaluate combined assay of serum Leptin,TNF-α,SOD in diagnosis and prognosis of nonalcoholic steatohepatitis(NASH).Method:Chemical and radio immunoassay were used to determine the level changes of Leptin,TNF-α and SOD.Results:(1) Compared with the normal control group(3.533±1.686ng/ml),serum Leptin levels were significantly elevated(P0.05)in the nonalcoholic simple fatty liver (NASFL) group(8.068±2.320ng/ml)and the nonalcoholic steatohepatitis(NASH)group(13.320±5.323ng/ml).Level of Leptin was much higher in the NASH group than in the NASFL group(P0.05).(2)Serum TNF-α was much higher in the NASH group(0.322±0.165ng/ml)than in the normal control group(0.254±0.093ng/ml P0.05)and the NASFL group(0.271±0.098ng/ml).There were no obviously differences in serum TNF-α between the normal control group and the NASFL group(P0.05).(3) Compared with the normal control group(112.200±7.978U/ml),level of SOD was significantly dropped(P0.05)in the NASH group(72.540±1.325U/ml).There were no obviously differences in serum SOD between the normal control group and the NASFL group(109.900±8.903U/ml,P0.05).Conclusion:Leptin 10.35ng/ml with higher level TNF-αand lower SOD was useful marker for diagnosis of NASH." @default.
- W2391931738 created "2016-06-24" @default.
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- W2391931738 date "2005-01-01" @default.
- W2391931738 modified "2023-09-27" @default.
- W2391931738 title "Combined Assay of Serum Leptin、TNF-α、SOD In Diagnosis of Nonalcoholic Steatohepatitis" @default.
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