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- W2392011590 abstract "The cyclin-dependent kinase(CDK4) inhibitors were introduced,research progress in cyclin kinase was summed up.Synthesis routes of intermediate 2-bromo-1-(4-morpholinophenyl)-1-ethanone was studied.4-Fluoroacetophenone was used as raw material to synthesize 2-bromo-1-(4-morpholinophenyl)-1-ethanone by bromination reaction.Based on literatures,different synthesis routes were compared.The bromination-debromination synthesis route was finally chosen to synthesize target compound." @default.
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- W2392011590 date "2011-01-01" @default.
- W2392011590 modified "2023-09-26" @default.
- W2392011590 title "Design and Synthesis of Intermediate of the Cell Cycle Protein Kinase Inhibitors(CDKs)" @default.
- W2392011590 hasPublicationYear "2011" @default.
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