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- W2392064817 abstract "Objective To predict the B cell epitopes from tumor antigen MAGE-A sub-family,which could be used as the target in tumor immunotherapy.Methods Based on MAGE-A sub-family amino sequence combined with the analysis of the flexible regions of secondary structure of MAGE-A protein,the B cell epitopes of MAGE-A protein were predicted by methods of Kyte-Doolittle hydrophilicity plot,Emini,Karplus,and Jameson-Wolf.Results Five B cell epitopes derived from the tumor antigen MAGE-A sub-family were selected and some of them were highly similar or completely identical.Conclusion The combination of secondary structure prediction method and B cell prediction can improve the prediction efficiency and accuracy,which might be useful to develop some promising antigen peptide-based tumor vaccines." @default.
- W2392064817 created "2016-06-24" @default.
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- W2392064817 date "2009-01-01" @default.
- W2392064817 modified "2023-09-26" @default.
- W2392064817 title "Prediction of the common B cell epitopes derived from the tumor antigen MAGE-A sub-family" @default.
- W2392064817 hasPublicationYear "2009" @default.
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