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- W2392078596 abstract "Aim:To investigate the clinical effect of cerebellar fastigial nucleus electrical stimulation (FNS) in treatment of nonorganic insomnia.Methods:80 nonorganic insomnious patients who were diagnosed according to ICD-10 and 20 healthy controls without a sleep disorder were included. The patients with nonorganic insomnia were evaluated by actigraphy before and after c FNS treatment. And Pittsburgh sleep quality index (PSQI) and serum Orexin-A, Orexin-B levels were also detected.Results: Before FNS treatment, the actual wakeful time, sleep latency, mean sleep bout time in patients with nonorganic insomnia were significantly increased (P0.05); the sleep efficiency, mean length immobility were significantly decreased (P0.05); and the mean activity score, fragmentation index were significantly higher (P0.05), versus healthy controls. After FNS treatment, most parameters of actigraphy were improved, except assumed sleep, which were showed significant difference compared with before treatment(P0.05). And most parameters were no significant difference versus healthy controls(P0.05), except sleep efficiency and mean wake bout time. In addition, PSQI had the similar trend, whereas serum Orexin-A, Orexin-B levels among different groups were no significant difference(P0.05).Conclusion: The results demonstrate that cerebellar fastigial nucleus electrical stimulation may become a new therapy on nonorganic insomnia." @default.
- W2392078596 created "2016-06-24" @default.
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- W2392078596 date "2009-01-01" @default.
- W2392078596 modified "2023-09-23" @default.
- W2392078596 title "Clinical effects of Cerebellar fastigial nucleus electrical stimulation in treatment of nonorganic insomnia" @default.
- W2392078596 hasPublicationYear "2009" @default.
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