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- W2392088051 abstract "Objective To study the level of activated T lymphocytes in active stage of rheumatoid arthritis. Methods The expression of CD4 and CD134 in 20 patients with rheumatoid arthritis and in 11 healthy controls were detected by flow cytometry and specific monoclonal antibodies against CD4 and CD134.The CD4 positive, CD134 positive and CD4CD134 double positive cell numbers in the peripheral blood were calculated. Results In normal group: the positive rate of CD4 was (28.85±1.52)%, CD134 positive rate was (9.55±0.59)% ,and CD4CD134 double positive rate was (6.72±0.48)% .In RA group,CD4 positive rate was (34.39±1.33)%,CD134 positive rate was (15.92±1.14)% ,CD4CD134 double positive rate was(10.11±0.71)% . The data show significant difference: PCD4 = 0.0140, PCD134 = 0.0004, PCD4CD134 = 0.0025. Conclusion The level of activated T lymphocytes increased in active stage of rheumatoid arthritis. This study suggested that cellular immunity state might play a role in the pathogenesis of RA. Further study on cellular immunity in the pathogenesis of RA might be helpful for the development of ra-tionalble treatment for rheumatoid arthritis." @default.
- W2392088051 created "2016-06-24" @default.
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- W2392088051 date "2002-01-01" @default.
- W2392088051 modified "2023-09-24" @default.
- W2392088051 title "Examination and analysis of activated T lymphocytes in active stage of rheumatoid arthritis" @default.
- W2392088051 hasPublicationYear "2002" @default.
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