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- W2392105890 abstract "Objective To investigate the expression of PKB,NF-Bp65 and Bcl-xL in the lesions of psoriasis vulgaris.Methods Paraffin-embedded tissue sections from 30 psoriasis patients and 10 normal controls were analyzed by S-P immunohisto-chemistry technique for the expression of PKB,NF-Bp65 and Bcl-xL.PASI score of the psoriasis lesions are detected.The expressions of PKB,NF-Bp65 and Bcl-xL between patients with psoriasis were compared to that in normal controls.The relationship among the expression of PKB,NF-Bp65 and Bcl-xL was also analyzed.Results The expression and distribution of PKB,NF-Bp65 and Bcl-xL was statistically significant higher in lesional epidermis than that in epidermis of the controls(P0.05).There was significantly positive correlation between the level of PKB,NF-Bp65 and Bcl-xL expression in lesional epidermis and PASI score of patients(P0.01).There was significantly positive correlation between the expression of PKB and NF-B,PKB and Bcl-xL,NF-B and Bcl-xL in lesional epidermis(P0.01).Conclusions The expression of PKB,NF-Bp65 and Bcl-xL may be involved in the pathogenesis of psoriasis and has some relationship with the state of the severity of psoriasis." @default.
- W2392105890 created "2016-06-24" @default.
- W2392105890 creator A5011619008 @default.
- W2392105890 date "2010-01-01" @default.
- W2392105890 modified "2023-09-26" @default.
- W2392105890 title "Expression of PKB,NF-κBp65 and Bcl-xL in Psoriasis and the Relationship with It" @default.
- W2392105890 hasPublicationYear "2010" @default.
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