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- W2392114465 abstract "Objective:To study the inhibiting effect of continuous low-dose-rate irradiation to PC-3 transplanting tumor and to provide theory guidance.Methods: Two 125I seeds with liner arrangement of implanting modal for PC-3 prostate carcinoma.The tumor growth delay was investigated between experiment group and control group after continuous low dose rate irradiation for 48h,96h and 192h.Measure the size of tumor diameter and perpendicular diameter every two days and calculated the volume.The histological and pathological analysis were observed after different time and distance of 125I seed group and dummy seed group.Results: 125I seed continuous low dose irradiation could inhibit PC-3 tumor cell proliferation after different periods,the 96h group showed significant difference(P0.05.The histological and pathological analysis showed that 125I seed continuous low dose irradiation could induce PC-3 cells necrosis near 125I seed and the inhabitation effect became weak with the increasing of distance from center of 125I seed,there was no any reaction of dummy seed group.Conclusion: 125I seed continuous low dose radiation could inhibit the PC-3 tumor cells proliferation and induce tumor cells necrosis." @default.
- W2392114465 created "2016-06-24" @default.
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- W2392114465 date "2009-01-01" @default.
- W2392114465 modified "2023-09-22" @default.
- W2392114465 title "The inhibiting effect of continuous low-dose-rate ~(125)I seed radiation to prostate transplanting carcinoma" @default.
- W2392114465 hasPublicationYear "2009" @default.
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