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- W2392116022 abstract "Objective To explore the clinical efficacy of atropine and naloxone micropump continuous injection in the treatment of 25 cases of severe acute organophosphorus pesticide poisoning with respiratory failure.Methods 50 cases of organophosphorus pesticide poisoning patients with respiratory failure double-blind randomly divided into treatment group and control group,each with 25 cases.Treatment group was given atropine plus naloxone microinfusion pump injection at the basis of conventional therapy,the control group was only with interval intravenous atropine injection.Two groups of patients were maintain atropine status of 7-10 d or longer,at the same time with gastric lavage,pralidoxime chloride and mechanical ventilation when necessary.Observed two groups of patients with atropine total drug administration,time of atropine,treatment time,respiratory failure occurred and mortality.Results Time of atropine,time of respiratory failure occurrence,mortality,inadequate dose of atropine and rebound the incidence in treatment was decreased significantly compared with the control group (P0.05 or 0.01).Conclusion Micropump injected atropine and naloxone treatment feature with fast,adequate,constant and effective and easy administration,it can shorten the time of atropine,reduce mortality,inadequate dose of atropine and incidence of rebound,combined with naloxone can effectively control the occurrence of respiratory failure." @default.
- W2392116022 created "2016-06-24" @default.
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- W2392116022 date "2010-01-01" @default.
- W2392116022 modified "2023-09-23" @default.
- W2392116022 title "Atropine and naloxone micropump injection in treatment of 25 cases of organophosphorus pesticide poisoning with respiratory failure" @default.
- W2392116022 hasPublicationYear "2010" @default.
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