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- W2392184034 abstract "The newcastle disease virus antigen was prepared using chicken embryos inoculated with the NDV La Sota strain.The infectious bural disease virus antigen was prepared with the chicken embryo fibroblast inoculated with the IBDV BJQ902 cell adapted strain.The four batches of combined oil-emulsion vaccines were developed with these inactivated viruses in certain proportion.Its physical characteristics,sterility,safety,stability and efficacy were tested.The results proved that the vaccine was germfree,milky white,well-diatributed,W/O/W pattern.Its viscosity was 1.0-1.2 second,and more than 99% of vaccine particle were 1 μm,few were 2 μm-3 μm.The liquid height of tube bottom below 0.5 mm.In the safety test,the 28-day-old SPF chickens were inoculated with the 4 batches of vaccines,the local and whole body harmful effects were not observed in the following 14 days.In the efficiency test of ND,3 weeks after vaccination,the HI antibody titer against ND was 3.0-3.6 log2 and the protection rate was 9/10,9/10 and 10/10,respectively.In the efficiency test of IBD,28 days after vaccination,the neutralization antibody titer against IBD was 20 171,24 578 and 26 616 and the protection rate was 9/10,10/10,10/10 and 10/10,respectively.The test results showed that 3 batches of vaccines met the quality standards." @default.
- W2392184034 created "2016-06-24" @default.
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- W2392184034 date "2009-01-01" @default.
- W2392184034 modified "2023-09-22" @default.
- W2392184034 title "Preparation and Test of ND-IBD Combined Inactivated Vaccine" @default.
- W2392184034 hasPublicationYear "2009" @default.
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