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- W2392186598 abstract "Objective To evaluate the efficacy and side effects of cisplatin with recombinant mutant human tumor necrosis factor(rmhTNF)for malignant pleural effusions(MPE).Methods The clinical data of 54 patients with non-small cell lung cancer complicated with MPE were analyzed retrospectively.Group A were treated by cisplatin,and group B were by combination therapy with rmhTNF and cisplatin.The curative effects were compared.Results The total effective rate(CR+PR)of group A of 31 cases was 58.06%,the total effective rate(CR+PR)of group B of 23 cases was 86.96%.The total effective rate of group B was higher than that of group A,the difference between the two was statistically significant(χ2=5.286,P=0.021).Conclusion The recombinant modified human tumor necrosis factor(rmhTNF)and cisplatin have a synergistic effect,so the combination therapy can be used as an optimal treatment for patients with non-small cell lung cancer complicated with MPE,and its efficacy is superior to cisplatin alone." @default.
- W2392186598 created "2016-06-24" @default.
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- W2392186598 date "2010-01-01" @default.
- W2392186598 modified "2023-09-26" @default.
- W2392186598 title "Curative Efficacy of Recombinant Mutant Human Tumor Necrosis Factor for Malignant Pleural Effusions in Patients with Lung Cancer" @default.
- W2392186598 hasPublicationYear "2010" @default.
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