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- W2392218273 abstract "Objective To observe the effect of alprostadil injection in the treatment of coronary heart disease combined with peripheral arterial occlusive disease. Methods A total of 98 patients admitted in cardiovascular department of our hospital from June 2010 to June 2012 were selected and divided into treatment group (n=54) and control group (n=44). All patients were given conventional treatment including nitrate esters, angiotensin-converting enzyme inhibitors (ACEI), furosemide, calcium channel blocker, beta-blocker, aspirin, lipid-modulating drugs, etc. The treatment group added alprostadil injection 10 μg and normal saline 20 mL by intravenous drip, once a day for 2 weeks. Results Compared with the patients in control group, the 6-minute walking distance of the treatment group patients increased significantly, plasma HCY levels significantly reduced, ABI increased significantly, and the metabolic equivalants (METs) of Bruce treadmill exercise testing increased significantly. All the differences had significance (P 0.05). But cardiac output of two group patients had no statistically significant difference (P 0.05). Conclusion Alprostadil injection has definite effect in the treatment of coronary heart disease combined with peripheral arterial occlusive disease, and has no obvious adverse reactions." @default.
- W2392218273 created "2016-06-24" @default.
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- W2392218273 date "2013-01-01" @default.
- W2392218273 modified "2023-09-23" @default.
- W2392218273 title "Effect of alprostadil injection in the treatment of coronary heart disease combined with peripheral arterial occlusive disease" @default.
- W2392218273 hasPublicationYear "2013" @default.
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