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- W2392240190 abstract "Objective To study the relationship between clinical intervention and prognosis of cognitive impairment in the patients at different periods after mild or moderate traumatic brain injury.Methods Retrospective analysis was conducted to 180 patients with mild or moderate traumatic brain injury and cognitive impairment.They were randomly divided into treatment group A,treatment group B and control group.The treatment group A received donepezil hydrochloride,the treatment group B huperzine A,while the control group piracetam.The treatment cycle was 12 weeks.The Mini Mental Status Examination(MMSE),Wisconsin Card Sorting Test(WCST) and Glasgow Coma Scale(GOS) were employed to evaluate the efficacy before treatment,immediately after treatment,and 3 months after treatment.Results After 12 weeks,the MMSE and WCST scores were improved.The MMSE and WCST scores were better in the treatment group than in the control group.The GOS prognosis was better in the treatment group A than in the treatment group B.Three months after the treatment,the MMSE,WCST scores and GOS prognosis showed significant differences between the 3 groups.The treatment group A got the best efficacy.Conclusion The donepezil hydrochloride can significantly improve cognitive impairment and have effect on the long-term prognosis in the patient with mild or moderate traumatic brain injury." @default.
- W2392240190 created "2016-06-24" @default.
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- W2392240190 date "2012-01-01" @default.
- W2392240190 modified "2023-09-24" @default.
- W2392240190 title "A clinical study on the cognitive impairment in patients with mild or moderate traumatic brain injury" @default.
- W2392240190 hasPublicationYear "2012" @default.
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