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- W2392245612 abstract "Objectve: to explore the changes of NGF and BDNF in neurons of ventral horn in different time following crushed spinal cord injury(cSCI). Method: immunohistochemical ABC method was used to explore the changes of NGF and BDNF in neurons of ventral horn in different time following cSCI. Results: the results showed that NGF and BDNF positive products were mainly observed in neurons of ventral horn in intact group. After cSCI, Although the number of NGF positive neurons increased in 1?d group and 7d group, there is no statistical significance compared with intact group(P0 05). However, in 21?d group following injury, the numbers of NGF positive neurons more apparently increased than those of control group, 24?h group and 7?d group(P0 05). Compared with NGF, the numbers of BDNF positive neurons more greatly increased in 24?h following injury than those of control group and this change was kept to 21?d following injury. Conclusion: the expression of NGF and BDNF was upregulated at different time following injury. It indicated that NGF and BDNF not only involves in the physiological function of spinal cord in adult rat but also may play an important role in the processes of nerve injury following cSCI." @default.
- W2392245612 created "2016-06-24" @default.
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- W2392245612 date "2002-01-01" @default.
- W2392245612 modified "2023-10-10" @default.
- W2392245612 title "The Changes of Expression on NGF and BDNF in Neurons of Ventral Horn Following Crushed Spinal Cord Injury" @default.
- W2392245612 hasPublicationYear "2002" @default.
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