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- W2392255798 abstract "Objective To study the Aloe gel effect on radioactive dermatitis in rats in molecular level. Method The rats models of radioactive dermatitis vesicular reaction was established firstly. The rats were divided at random into 2 groups, with the normal healing group as the control group. Aloe gel was used on the radioactive dermatitis vesicular reaction of rats as the experimental group. Then 6th, 10th, 18th, 24th day post-injury, the protein of ICM-1 and EGF were stained by immunohistochemistry and analyzed. The wound-formation rate was measured too. Results Expression of CM-1: the total expression of ICM-1 in experimental groups was significantly lower than control groups. So did at 2nd, 4th days. Expression of EGF: the total expression of EGF in experimental groups was significantly higher than that of control groups. So did at 10th and 18th day. The wound formation rate of experimental group was lower significantly than that of the control group. Conclusions The Aloe gel exerts protective effect on the ICM-1 at early stage of radioactive dermatitis vesicular reaction. The Aloe gel can accelerate the expression of EGF of radioactive dermatitis vesicular reaction. The significant expression is at middle stage of the wound healing. The Aloe gel can control radioactive dermatitis vesicular reaction" @default.
- W2392255798 created "2016-06-24" @default.
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- W2392255798 date "2006-01-01" @default.
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- W2392255798 title "Study of Aloe gel effect on expression of ICM-1 and EGF in dermatitis by radiation in rats" @default.
- W2392255798 hasPublicationYear "2006" @default.
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