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- W2392283749 abstract "Nineteen curcumin analogs were designed and synthesized from aromatic aldehydes and 4-piperidone by claisen-schmidt condensation.Their structures were characterized by 1H-NMR and MS.Their antitumor activities in vitro were evaluated against K562 and SW1116 tumor cell Lines by MTT assay.The results showed that compounds 1,2,3,4,5,9,14,18 had significantly better activity against K562 cells than EF-24(IC50=1.58 μmol·L-1).Compounds 7,10,11 were stronger than EF-24(IC50=11.7 μmol·L-1)on SW1116." @default.
- W2392283749 created "2016-06-24" @default.
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- W2392283749 date "2011-01-01" @default.
- W2392283749 modified "2023-09-26" @default.
- W2392283749 title "Synthesis and antitumor activity in vitro of curcumin analogs" @default.
- W2392283749 hasPublicationYear "2011" @default.
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