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- W2392293065 abstract "Objective To investigate and analyze the efficacy and adverse reactions of telmisartan administered at different time points for the treatment of patients with non-dipper hypertension. Methods 170 cases with mild or moderate non-dipper hypertension were selected strictly and randomly divided into the morning medication group(83 cases) and evening medication group(87 cases). Both groups were given the same dose of telmisartan(angiotensin Ⅱ receptor antagonist) once a day for treatment, the morning medication group was given telmisartan 80 mg at eight in the morning, and the evening medication group was given telmisartan 80 mg at eight in the evening. The ambulatory blood pressure of the two groups of patients were monitored after 12 weeks of continuous administration for assessing the difference in circadian blood pressure rhythm. Results Both groups had patients with non-dipper hypertension transforming into dipper hypertension, the number turnover of the morning medication group was 21%, and that of the evening medication group was 53%, the difference between the two groups was statistically significant(P0.05). Both groups of patients suffered mild adverse reactions during the period of taking telmisartan but needed not special treatment. And there was no statistically significant difference in the incidence of adverse reactions between the two groups.Conclusion This study indicates that telmisartan can treat non-dipper hypertension with significant effect, and the curative effect will be better if it is administered in the evening, which can provide an effective reference for selecting the time of medication clinically." @default.
- W2392293065 created "2016-06-24" @default.
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- W2392293065 date "2014-01-01" @default.
- W2392293065 modified "2023-09-28" @default.
- W2392293065 title "Comparative Analysis of Administration of Telmisartan at Different Times for the Treatment of Non-dipper Hypertensive Patients" @default.
- W2392293065 hasPublicationYear "2014" @default.
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