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- W2392297704 abstract "Objective To assess the relationship between glucocorticoid receptor (GR) and its α Isoforms (GRα) and hemangioma(H) and vascular malformation(VM). Methods sections of 33 proliferative hemangioms, 32 involuting hemangiomas and 7 vascular malformations were immunostained for GR and GRα. Results The GR-positive gray scale in hemangioms, vascular malformations, normal skin were ((126.95)±(6.41))、((121.43)±(6.58)) and ((108.63)±(6.80)) respectively. There was no difference between hemangiomas and vascular malformations. But the difference between hemangioms (P(0.01)), vascular malformations (P(0.01)) and normal skin was significant. The GRα-positive gray scale in hemangiomas, vascular malformations, normal skin were ((127.32)±(5.36))、((120.43)±(6.13)) and ((109.88)±(5.28)) respectively. There was a significant difference between one another. The GR-positive gray scales were ((127.91)±(4.81))、((125.97)±(5.78)), and GRα’s were ((127.55)±(6.41))、((122.47)±(6.25)) in proliferative involuting hemangiomas respectively. There was no difference in GR. The difference in GRαexpression between proliferative and involuting hemangiomas was significant. Conclusions GR and GRαare expressed in hemangioma and vascular malformation. The expression of GRαis closely related to the stage of hemangiomas. GR and GRαexpressions provide a guidance for steroid management in hemangioma and vascular malformation." @default.
- W2392297704 created "2016-06-24" @default.
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- W2392297704 date "2005-01-01" @default.
- W2392297704 modified "2023-09-26" @default.
- W2392297704 title "Glucocorticoid receptor isoforms in hemangioma and vascular malformation" @default.
- W2392297704 hasPublicationYear "2005" @default.
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