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- W2392303554 abstract "To enhance bioavailability and improve its palatability of berberine,alcohol formulation was used to extract berberine fromRhizoma coptidis,then the method of drying in fluid was used to prepare the berberine enteric microcapsule.The single factor experiments was used to observe the several key conditions affecting the formation of the microcapsule.The optimum conditions for the preparation of berberine enteric microcapsules are as follows:berberine∶HPMCP is 1∶7,HPMCP∶the mixture liquid of acetone and alcohol is 1∶20,the mixture liquid of acetone and alcohol∶liquid paraffin is 1∶5,Span 80∶liquid paraffin is 6∶100.The microcapsules prepared has uniform appearance,with an average particle size of 30.54μm ranging 5-55μm,and with an average encapsulation efficiency of 93.32%.The dissolution rate of microcapsule in artificial gastric juice for 2hwas less than 2%,in the artificial intestinal juice for 2hreleased 97.343%,complied with the requirement of Chinese pharmacopoeia." @default.
- W2392303554 created "2016-06-24" @default.
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- W2392303554 date "2014-01-01" @default.
- W2392303554 modified "2023-09-23" @default.
- W2392303554 title "Preparation of berberine enteric microcapsules" @default.
- W2392303554 hasPublicationYear "2014" @default.
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