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- W2392347919 abstract "Objective To investigate the effects of Berberine and Matrine,both of which are active components from Chinese materia medica,against the formation of mixed bacteria biofilms of vulvovaginal candidiasis in vitro.Methods Mixed biofilms of Monilia albicans and Pseudomonas aeruginosa were developed in vitro.Tetrazolium salt(XTT) reduction assay and morphological methods were employed to observe the formation process of mixed Monilia albicans and Pseudomonas aeruginosa.The sessile minimal inhibitory concentration(SMIC) of Berberine and Matrine on mixed biofilms of Monilia albicans was evaluated using morphological methods and colony-forming unit(CFU) counting.Results Monilia albicans formed mature biofilms after being cultured for 48 hours.Berberine 125 mg/L could inhibit the formation of mixed Monilia albicans.Matrine 500 mg/L was not found to inhibit the formation of mixed Monilia albicans.Conclusion Berberine can be used for preventing vulvovaginal candidiasis because of its inhibitive effects against the formation of biofilms." @default.
- W2392347919 created "2016-06-24" @default.
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- W2392347919 date "2012-01-01" @default.
- W2392347919 modified "2023-09-27" @default.
- W2392347919 title "Effects of Berberine and Matrine against Formation of Mixed Biofilms of Vulvovaginal Candidiasis" @default.
- W2392347919 hasPublicationYear "2012" @default.
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