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- W2392389727 abstract "ObjectiveTo study the correlation between the TCD parameters,intracranial pressure(ICP) and cerebral perfusion pressure(CPP) in acute diffuse intracranial hypertension model of rabbits.Methods The experiments were performed on the twelve rabbits(Group B),which were continuously infused Ringer's solution via the cisterna magna while in control group(Group A) were not.ICP、HR、MAP、R and TCD parameters before and every 15 minutes after puncture were monitored,then the CPP was calculated out.Results In Group A,there was no significant difference before and after puncture.In Group B,there were closely linear correlations between the changes of the TCD parameters and ICP,or TCD parameters and CPP.The changes of the TCD happened before the changes of vital signs,when were more earlier than the Cushing's reaction occurred.In the protophase before death,rebounding phenomenon occurred in TCD,in which 83.3% died.Conclusions In the acute diffuse intracranial hypertension rabbit model,the changes of the TCD can reveal the variations of ICP and CPP in advance.The special rebounding phenomenon occurs in later stage of intracranial hypertension,which highly illustrates poor prognosis." @default.
- W2392389727 created "2016-06-24" @default.
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- W2392389727 date "2008-01-01" @default.
- W2392389727 modified "2023-09-24" @default.
- W2392389727 title "Relation between Transcranial Doppler,Intracranial Pressure and Cerebral Perfusion Pressure of Acute Diffuse Intracranial Hypertension in Rabbits" @default.
- W2392389727 hasPublicationYear "2008" @default.
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