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- W2392463589 abstract "OBJECTIVE To investigate the separating capacity of Sephadex gel for dexamethasone-loaded nanoparticles.METHODS Single factor tests and central composite design-response surface methodology were employed for optimization of chromatographicparameters,and the established conditions were adopted to validate the encapsulation efficiency of dexamethasone-loaded nanoparticles.RESULTS The optimal eluting condition was as follows: the ratio of diameter to height was 0.23,flowrate was 0.52 mL·min-1,and the amount of loaded drug was 41 μg.These paration degree reached 79.01%.CONCLUSION Sephadex gel can be utilized properly to separate free drug from dexamethasone-loaded nanoparticles." @default.
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- W2392463589 date "2012-01-01" @default.
- W2392463589 modified "2023-09-23" @default.
- W2392463589 title "Determining the Encapsulation Efficiency of Dexamethasone-Loaded Nanoparticles Using Sephadex Gel Column Chromatography" @default.
- W2392463589 hasPublicationYear "2012" @default.
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