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- W2392471318 abstract "Hypericin is a virucidal agent with activity against cancer and a broad range of viruses. However, its pharmacology and mechanism of action are still unclear. This investigation focus on the possible inhibits activity of hypericin on HIV-1 protease(HIV-IP) function and related pathways. Results indicate that hypericin is rigidly held in the catalyst active site of HIV-1P close to the catalyst residues of ASP-A25 and ASP-B25 with hydrogen bond interaction. These results may provide insights for study on antivirus activity of traditional Chinese medicine." @default.
- W2392471318 created "2016-06-24" @default.
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- W2392471318 date "2009-01-01" @default.
- W2392471318 modified "2023-09-25" @default.
- W2392471318 title "Studies on Molecular Structure of Hypericin and Its Interactions with HIV-1 Protease by Molecular Modeling" @default.
- W2392471318 hasPublicationYear "2009" @default.
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