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- W2392479008 abstract "In order to identify Tpo as the autocrine growth factor of human erythroleukemic cell line (HEL cells). non-radioactive in situ hybridization was used to detect mRNAs of Tpo and c-mpl, indirect immunofluorescence and biotin-avidin system were used to detect Tpo and Mpl, a cytosensor was used to analyze the electronic voltammetric behavior (EVB) of HEL cells. Results indicated: Mpl as a membrane receptor on HEL cells, Tpo protein existing in HEL cells, rhTpo promoting proliferation of HEL cells and Mpl-IgG blocking the proliferation of HEL cells. After the Mpl-IgG blocking, EVB of HEL cells decreased, but there was still a discordance between cell count and EVB of HEL cells. It was concluded that Tpo may be a possible autocrine factor of HEL cells." @default.
- W2392479008 created "2016-06-24" @default.
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- W2392479008 date "1998-01-01" @default.
- W2392479008 modified "2023-09-25" @default.
- W2392479008 title "Thrombopoietin is a possible autocrine growth factor of HEL cell line" @default.
- W2392479008 hasPublicationYear "1998" @default.
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