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- W2392544094 abstract "AIM To investigate the relationship between MALT hyperplasia and gastric mucosal atrophy induced by H.pylori and to assess the lymphoid follicles (LF) after eradication of H.pylori . METHODS Aggregation intensity and detectable rate of LF one month and one year after eradication of H.pylori (triple therapy, i.e. omeprazole, clarithromycin and furazolidone for 7 days) were obtained by microscopic observation of gastric biopsy specimens from 25 normal persons and 258 chronic gastritis patients and compared with before triple therapy. RESULTS In patients with chronic gastritis, the prevalence of lymphoid follicles was 72 5% as a whole, and the positive rate in atrophic gastritis was higher than that in superficial gastritis. The frequency of LF detection in the normal ones was only 4%. The prevalence of lymphoid follicles was correlated strongly with the mucosa inflammation ( r =0 65, P 0 01) and the severity of the atrophy ( r =-0 69, P 0 01). Eradication of H.pylori resulted in the decrease of follicles ( P 0 01), and the lymphoid follicles were correlated with the gastric mucosal atrophy. CONCLUSION Gastric MALT hyperplasia and its associated immunoreaction may be one of the important causes of the destruction of gastric glands in the H.pylori associated gastritis." @default.
- W2392544094 created "2016-06-24" @default.
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- W2392544094 date "1998-01-01" @default.
- W2392544094 modified "2023-09-24" @default.
- W2392544094 title "Relationship between gastric MALT hyperplasia and Hp induced atrophy" @default.
- W2392544094 hasPublicationYear "1998" @default.
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