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- W2392628037 abstract "OBJECTIVE To study the mobilizing effects of salviolⅡA and paeonol combination(Group of formula)on bone marrow stem cells(BMSCs)in cerebral ischemia injury of rats.METHODS The cerebral ischemia model was established by using nylon thread approach.Neurological function scores,the infarct volume,water content and the pathological changes of ischemic cerebral tissues were determined.Peripheral leukocytes(WBC)and mononuclear cells(MNC)were measured by blood cell analyzer.The expression of peripheral blood CD34+cells was determined using flow cytometry.RESULTS Formula and rhG-CSF-jointed formula groups both significantly improved the neurological function scores of cerebral ischemic rats and reduced infarct volume and water content.Comparing with model control group,the WBC and MNC cells of treated rats increased,no statistical difference was observed,however.The expression of peripheral blood CD34+cells were significantly increased by the rhG-CSF-jointed formula(P0.05).Pathological observations indicated rhG-CSF-jointed formula group could protect the cerebral ischemia injury in rats.CONCLUSION The rhG-CSF-jointed formula promoted the mobilization of bone marrow stem cells,further to increase the protective effects on cerebral ischemia." @default.
- W2392628037 created "2016-06-24" @default.
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- W2392628037 date "2014-01-01" @default.
- W2392628037 modified "2023-09-25" @default.
- W2392628037 title "Mobilizing effects of salviolII_A and paeonol combination on bone marrow stem cells in cerebral ischemia injury of rats" @default.
- W2392628037 hasPublicationYear "2014" @default.
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