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- W2392632004 abstract "Objectives We sought to compare the effects of anticoagulation therapy on the patients with unileaflet or bileaflet mechanical prosthetic valve (MPV) associated with identity intensity of anticoagulation. Methods 214 patients were evaluated for eligibility to enter the trial: 118 patients received bileaflet MPV (CarboMedics, St.Jude.group A) and 96 patients received unileaflet MPV (Lanzhou, Shanghai. group B). Anticoagulation with oral warfarin (Espoo product) was at an INR range 1.5～2.3 for each patients, warfarin dose range was 0.75～4 mg/day [mean (1.94±1.16) mg/day]. Follow-up study were performed on all patients during 3～84 months [mean (39.86±16.28) months]. The rates of thrombembolic and anticoagulation associated bleeding were compared. Results 6 patients in the group A and 5 patients in the group B had bleeding complication events. 1 patient in the group A and 8 patients in the group B had thrombembolic events. Conclusions An INR of 1.5～2.3 is recommended to protect patients who recipiented bileaflet MPV form developing a complication of bleeding or thrombembolia. However, the risk of thrombembolia would be increased in the patients who recipiented unileaflet." @default.
- W2392632004 created "2016-06-24" @default.
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- W2392632004 date "2004-01-01" @default.
- W2392632004 modified "2023-09-26" @default.
- W2392632004 title "A clinical comparative study on effects of anticoagulation therapy for the patients implanted unileaflet or bileaflet mechanical prosthetic valves" @default.
- W2392632004 hasPublicationYear "2004" @default.
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