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- W2392654164 abstract "Objective To investigate the changes of fasting serum leptin and insulin level in obstructive sleep apnea-hypopnea syndrome (OSAHS) patients and to study the correlation between serum leptin level and insulin resistance in OSAHS patients.Methods Polysomnography was examined during sleep,and fasting plasma glucose,serum leptin level and insulin level were determined in 50 OSAHS patients and 50 age-matched normal controls.Results (1)Compared with control subjects,serum leptin level,fasting insulin level and HOMA-IR were significantly higher in OSAHS patients.(2)In OSAHS patients,serum leptin level,fasting insulin level and HOMA-IR were positively correlated with AHI,the longest apnea/hypopnea duration and microarousal index,and negatively correlated with the minimum oxygen saturation.(3)In OSAHS patients,serum leptin level was positively correlated with fasting insulin level and HOMA-IR.Conclusion (1)Serum leptin level was significantly higher in OSAHS patients,and serum leptin level was correlated with the severity of OSAHS.(2)OSAHS might correlate with insulin resistance of BMI independently.(3)Serum leptin level was correlated with insulin resistance in OSAHS patients." @default.
- W2392654164 created "2016-06-24" @default.
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- W2392654164 date "2005-01-01" @default.
- W2392654164 modified "2023-09-23" @default.
- W2392654164 title "The Level of Serum Leptin and the Correlation with Insulin Resistance in OSAHS Patients" @default.
- W2392654164 hasPublicationYear "2005" @default.
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