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- W2392722992 abstract "Objective To investigate the correlation between the quantity of HCV-RNA (detected by Real-time Fluorescent Quantitative PCR) and concentrations of anti-HCV and alanine transaminase (ALT). Methods The quantify of HCV-RNA in 115 serum samples were detected by fluorescent quantitative PCR (FQ-PCR), the concentrations of anti-HCV and ALT were detected by Enzyme immunoassay and automatic biochemistry analyzer. Results In 63 of 115 serum samples, the quantity of HCV-RAN was more than 80 copies per milliliter (the positive rate of HCV-RNA was 54.8%); the positive rate of anti-HCV was 53.9%(62/115); the ALT in 40.9 percent of samples (47/115) was abnormal. It was positive correlation between quantity of HCV-RNA and the number of anti-HCV positive samples (r=0.986, P0.01). It was positive correlation between the quantity of HCV-RNA and the number of samples with abnormal ALT (r=0.94, P0.01), and the same between quantity of HCV-RNA and content of ALT(r=0.624, P0.01). Conclusions It is positive correlation between the quantity of HCV-RNA and the positive rate of anti-HCV, abnormal rate of ALT, content of ALT. FQ-PCR can be a method of diagnosing hepatitis C." @default.
- W2392722992 created "2016-06-24" @default.
- W2392722992 creator A5062005105 @default.
- W2392722992 date "2005-01-01" @default.
- W2392722992 modified "2023-09-27" @default.
- W2392722992 title "Detection of Hepatitis C virus RNA by Real-Time Fluorescent Quantitative PCR" @default.
- W2392722992 hasPublicationYear "2005" @default.
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