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- W2392729773 abstract "Objective:To investigate the effects of oridonin-induced apoptosis and expression of P53 on LOVO cells.Methods:Cell proliferation of oridonin on LOVO cell was determined by CCK-8 assay.Apoptosis rate and expression of P53 were analysed by Flow Cytometry(FCM).ResuIts:CCK-8 assay showed that oridonin had a moderate anti-proliferation effect on LOVO cells in a time-dependant and dose-dependant manner.LOVO cells treated with 8,5 and 1.5 μmol/ml for 48 hours and the apoptosis rate were 35.8%,26.6% and 17.4% respectively(P0.05,P0.01).The expression of P53 were 48.4%,44.6% and17.4% respectively(P0.01).Conclusion: Oridonin had obvious inhibitory effects on LOVO cells in a dosedependant manner.Oridonin apoptosis-induced related with P53." @default.
- W2392729773 created "2016-06-24" @default.
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- W2392729773 date "2011-01-01" @default.
- W2392729773 modified "2023-09-27" @default.
- W2392729773 title "Oridonin Induced Apoptosis and Expression of P53 on LOVO Cells" @default.
- W2392729773 hasPublicationYear "2011" @default.
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