Matches in SemOpenAlex for { <https://semopenalex.org/work/W2392755563> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2392755563 abstract "Objective To study the effects of recombinant human erythropoietin(rhEPO)on microglia in rat model of Parkinson's disease induced by 6-hydroxydopamine(6-OHDA).Methods Forty SD rats were randomly divided into four groups:A group(rhEPO+6-OHDA),B group(saline+6-OHDA),C group(6-OHDA)and D group(saline),ten average each group.Related manipulation:A group,ipsilateral substantia nigra(SN)stereotactic rejection of 6-OHDA on 24h after right striatum stereotactic rejection of rhEPO;B group,ipsilateral SN stereotactic rejection of 6-OHDA on 24h after right striatum stereotactic rejection of saline(equal quantity of rhEPO);C group,right SN stereotactic rejection of 6-OHDA;D group,right SN stereotactic rejection of saline(equal quantity of 6-OHDA).All groups were detected 4 weeks after the operation about the numbers of tyrosine hydroxylase(TH)positive neurons and morphological changes of CD11b positive cells in the SN by immunohistochemistry.Results Compared with D group,the number of TH+ neurons of SN reduced greatly in A group,the number of CD11b+ cells in SN increased markedly and most microglia showed small cell body with slim and long processes in A group.Compared with B and C group,the number of TH+ neurons in SN increased remarkably in A group,the number of CD11b+ cells of SN decreased markedly and only a few microglia showed big cell body with thicker shorter processes in A group.Conclusion Probably through blocking activation of microglia,rhEPO could prevent 6-OHDA-induced degeneration of DA neurons and protect DA neurons." @default.
- W2392755563 created "2016-06-24" @default.
- W2392755563 creator A5089545689 @default.
- W2392755563 date "2010-01-01" @default.
- W2392755563 modified "2023-09-28" @default.
- W2392755563 title "Effects of recombinant human erythropoietin on microglia in rat model of Parkinson's disease" @default.
- W2392755563 hasPublicationYear "2010" @default.
- W2392755563 type Work @default.
- W2392755563 sameAs 2392755563 @default.
- W2392755563 citedByCount "0" @default.
- W2392755563 crossrefType "journal-article" @default.
- W2392755563 hasAuthorship W2392755563A5089545689 @default.
- W2392755563 hasConcept C126322002 @default.
- W2392755563 hasConcept C134018914 @default.
- W2392755563 hasConcept C142724271 @default.
- W2392755563 hasConcept C159167319 @default.
- W2392755563 hasConcept C170493617 @default.
- W2392755563 hasConcept C171779818 @default.
- W2392755563 hasConcept C204232928 @default.
- W2392755563 hasConcept C2776914184 @default.
- W2392755563 hasConcept C2777397205 @default.
- W2392755563 hasConcept C2778534260 @default.
- W2392755563 hasConcept C2779134260 @default.
- W2392755563 hasConcept C2779734285 @default.
- W2392755563 hasConcept C2779830541 @default.
- W2392755563 hasConcept C2780062018 @default.
- W2392755563 hasConcept C2780678043 @default.
- W2392755563 hasConcept C2780938664 @default.
- W2392755563 hasConcept C513476851 @default.
- W2392755563 hasConcept C71924100 @default.
- W2392755563 hasConceptScore W2392755563C126322002 @default.
- W2392755563 hasConceptScore W2392755563C134018914 @default.
- W2392755563 hasConceptScore W2392755563C142724271 @default.
- W2392755563 hasConceptScore W2392755563C159167319 @default.
- W2392755563 hasConceptScore W2392755563C170493617 @default.
- W2392755563 hasConceptScore W2392755563C171779818 @default.
- W2392755563 hasConceptScore W2392755563C204232928 @default.
- W2392755563 hasConceptScore W2392755563C2776914184 @default.
- W2392755563 hasConceptScore W2392755563C2777397205 @default.
- W2392755563 hasConceptScore W2392755563C2778534260 @default.
- W2392755563 hasConceptScore W2392755563C2779134260 @default.
- W2392755563 hasConceptScore W2392755563C2779734285 @default.
- W2392755563 hasConceptScore W2392755563C2779830541 @default.
- W2392755563 hasConceptScore W2392755563C2780062018 @default.
- W2392755563 hasConceptScore W2392755563C2780678043 @default.
- W2392755563 hasConceptScore W2392755563C2780938664 @default.
- W2392755563 hasConceptScore W2392755563C513476851 @default.
- W2392755563 hasConceptScore W2392755563C71924100 @default.
- W2392755563 hasLocation W23927555631 @default.
- W2392755563 hasOpenAccess W2392755563 @default.
- W2392755563 hasPrimaryLocation W23927555631 @default.
- W2392755563 hasRelatedWork W1121863226 @default.
- W2392755563 hasRelatedWork W1605537968 @default.
- W2392755563 hasRelatedWork W1964773062 @default.
- W2392755563 hasRelatedWork W1991343988 @default.
- W2392755563 hasRelatedWork W2365280488 @default.
- W2392755563 hasRelatedWork W2369248918 @default.
- W2392755563 hasRelatedWork W2372481149 @default.
- W2392755563 hasRelatedWork W2372717799 @default.
- W2392755563 hasRelatedWork W2375692226 @default.
- W2392755563 hasRelatedWork W2378600395 @default.
- W2392755563 hasRelatedWork W2381603644 @default.
- W2392755563 hasRelatedWork W2398172110 @default.
- W2392755563 hasRelatedWork W2414487866 @default.
- W2392755563 hasRelatedWork W2512095232 @default.
- W2392755563 hasRelatedWork W2559913182 @default.
- W2392755563 hasRelatedWork W2740821661 @default.
- W2392755563 hasRelatedWork W2911888944 @default.
- W2392755563 hasRelatedWork W2978267811 @default.
- W2392755563 hasRelatedWork W3031896514 @default.
- W2392755563 hasRelatedWork W3148274780 @default.
- W2392755563 isParatext "false" @default.
- W2392755563 isRetracted "false" @default.
- W2392755563 magId "2392755563" @default.
- W2392755563 workType "article" @default.