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- W2392804963 abstract "Objective Exploring the kinetics of IL-18,IL-4,IFN-γ in BALB/c mice systemically infected with Candida Albicans.Methods BALB/c mice were divided into 4 groups randomly:the high dose infected group,the low dose infected group,the low immunologic function group,the normal control group.ABC-ELISA was used to detect these mice immunological function after infected CA(Candida Albicans) at the 1~(st),4~(th),7~(th) day.Results The level of IL-18 sharply decreased at the first day,but still higher than that of the low immunologic function group(P0.05～0.001),and arrived to the normal level at the 7~(th) day.The level of IFN-γ always elevated over the normal group(P0.05) and the low immunologic function group(P0.01).IL-4 decreased comparing with the that in normal group post the first day,but still higher than that of the low immunologic function group(P0.05～0.001),having no difference with the normal control group at 4~(th) day,elevated with the normal group 7~(th) day later(P0.05).Conclusion When BLAB/c mice infected the high or low dose CA,the major immunological reaction of the organism was Th1 cytokines at early stage;The Th1/Th2 cytokines would elevated at the later stage,which showed the cellar immunity and humoral immunity took part in the response against the CA infection." @default.
- W2392804963 created "2016-06-24" @default.
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- W2392804963 date "2006-01-01" @default.
- W2392804963 modified "2023-09-28" @default.
- W2392804963 title "The Kinetics of IL-18,IL-4,IFN-γ in Sera in BALB/c Mice Systemically Infected with Candida Albicans" @default.
- W2392804963 hasPublicationYear "2006" @default.
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