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- W2392822062 abstract "Objective To study the effects of potassium antimonyl tartrat on human gastric cancer cells(SGC-7901) and to explore its possible mechanism.Methods Human gastric carcinoma cell line SGC-7901 was cultured in vitro. Potassium antimonyl tartrate of different concentrations was added into the media.Cell without adding potassium antimonyl tartrate was used as control. The growth inhibition of cells induced by various concentration in different time course was analyzed by using MTT assay;The cell were stained by Hoechst33258 and the morphologic changes were observed under fluorescence microscope.The apoptosis peak of the cells and the changes of cell cycle were analysed using flow cytomtery.Rusult SGC-7901cells was inhibited obviously by potassium antimonyl tartrate;Chromatin condensation and nuclear fragmentation were seen under fluorescence microscope in the cells stained with Hoechst 33 258.Apoptosis peak were also detected by flow cytometry ,the percentage of G 2/M cells increased significantly in the test group .Conclussion Potassium antimonyl tartrate significantly inhibits the proliferation of SGC-7901 cells." @default.
- W2392822062 created "2016-06-24" @default.
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- W2392822062 date "2004-01-01" @default.
- W2392822062 modified "2023-09-23" @default.
- W2392822062 title "Inhibition of human gastric cancer cell proliferation induced by potassium antimonyl tartrate" @default.
- W2392822062 hasPublicationYear "2004" @default.
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