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- W2392840903 abstract "Objective To explore individualized chemotherapy program of elderly acute leukemia.Methods 74 patients aged≥60 years with acute leukemia from 2000 to 2007 were analyzed retrospectively.The first dosage as induced remission program taken into account,the patients were divided into two groups(sub-standard dosage as group A and decreased dosage or low dose as group B).The clinic efficacy of the two groups were compared and analyzed.Results Patients that could be evaluated in group A were 24 cases and in group B were 19 cases.The complete remission(CR)of them were 37.5% and 26.31%.The total effective rates were respectively 62.5% and 73.68%,with a higher percentage in group B than in group A.The mean survival time were 176 days and 203 days respectively(P0.05).The bone marrow suppression duration time was 23 days and 14 days in group A and B respectively(P0.05).The side effect incidence for group A and group B was 91% and 87%(P0.05).Early death was higher in group A than in group B(chemotherapy-related death).Conclusion The response of acute leukemia of the elderly people to chemotherapy is relatively poor,and they have a lower CR rate and shorter overall survival time.The patients should be treated individually.The chemotherapy regimen of decreased dose or lowred dose is suitable for old age acute leukemia." @default.
- W2392840903 created "2016-06-24" @default.
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- W2392840903 date "2009-01-01" @default.
- W2392840903 modified "2023-09-26" @default.
- W2392840903 title "Clinical analysis and individualized treatment of old age acute leukemia" @default.
- W2392840903 hasPublicationYear "2009" @default.
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