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- W2392844327 abstract "Objective To investigate the anti-tumor immunoefficacy induced by HAC70 derived from Ehrlich ascites tumor cell and to study its clinical application.Methods After the heat-shock HSP70 from the Ehrlich ascites tumor cell was isolated and pureed by Heparin-Sepharose chromatography and got the HAC70 vaccine. The anti-tumor efficacy of splenocyte was determined by the3H-TdR release assay.Results The average tumor weight of the mice received HAC70 immunization was only 1.26±0.4 g,obvious difference(P0.05)observed when contrasted with the control group(3.14±0.56 g).It was showed that specific cytotoxitic rate of splenocytes from the immunized mice to the Ehrlich ascites tumor cells was 49.75±8.93%,significantly higher than from the tumor-bearing(18.5±9.95%)and control group(25.75±8.38,P0.01).Conclusion HAC70 pureed by Heparin-Sepharose chromatography have the activities of inflicting the Ehrlich ascites tumor cell and inhibit obviously growth of the Ehrlich ascites tumor." @default.
- W2392844327 created "2016-06-24" @default.
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- W2392844327 date "2007-01-01" @default.
- W2392844327 modified "2023-09-22" @default.
- W2392844327 title "The experiment study of inflict activies induced by HAC70 on Ehrlich ascites tumor cell" @default.
- W2392844327 hasPublicationYear "2007" @default.
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