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- W2392851740 abstract "Objective To evaluate the clinical effect of different methods in the treatment of major recurrent aphtha.Methods Ninety individuals with major recurrent aphtha were divided into three groups randomly.Chinese herbal medicine was applied to the first group,and thalidomide was applied to the second group.Both Chinese herbal medicine and thalidomide were applied to the third group.After four weeks and one year,the curative effect of the three groups were recorded and compared.Serum levels of TNF-α of three groups with major recurrent aphtha were tested and compared before and after treatment,and one year after treatment.Results There was a significant difference of total effective rate in three groups(P 0.05).The serum TNF-α level of the three groups respectively was(30.63 ± 3.91) μg / L,(32.06 ±4.26) μg/L and(31.48 ± 4.36) μg/L before treatment.The serum TNF-α level in the first group was(23.74 ±6.21) μg/L after four weeks and that was(25.45 ±7.16) μg/L after one year.The serum TNF-α level in the second group was(18.79 ± 4.41) μg / L after four weeks and that was(17.97 ± 5.55) μg / L after one year.The serum TNF-α level of the third group was(16.26 ± 5.31) μg / L after four weeks and that was(15.93 ± 5.74) μg / L after one year.The serum TNF-α level in third group was significantly reduced after treatment.There was a significant difference of the serum TNF-α level between the third group and the other two groups after treatment,either after four weeks or after one year(P 0.05).Conclusion Thalidomide with Chinese herbal medicine is effective to treat the major recurrent aphtha.It is worthing to extend its clinical application." @default.
- W2392851740 created "2016-06-24" @default.
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- W2392851740 date "2014-01-01" @default.
- W2392851740 modified "2023-09-28" @default.
- W2392851740 title "Comparison of effect on major recurrent aphtha with different methods of treatment" @default.
- W2392851740 hasPublicationYear "2014" @default.
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