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- W2392854639 abstract "Objective To investigate the effect of vinpocetine on human umbilical vein endothelial cells(HUVECs)lipid peroxidation induced by reactive oxygen species.Methods HUVECs were cultured in vitro with DMEM and 100 g·L-1 calf plasma.Different dose(10,20,50,100 μmol·L-1) of H2O2 were added to the HUVECs as extraneous reactive oxygen species.Effect of vinpocetine on the HUVECs proliferation were determined by 3H-TdR incorporation and cell cycle phase analysis after cells were preincubated with different dose(10,50,100 mmol·L-1) of vinpocetine.Results H2O2 exhibited dose-dependent ihibitory effect on the cell proliferative activity.Vinpocetine could inhibit the effect of H2O2 on the proliferation of HUVECs,also exhibited dose-dependence.Conclusion These results demonstrate that vinpocetine may have potential clinical implication in the prevention and treatment of atherosclerosis." @default.
- W2392854639 created "2016-06-24" @default.
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- W2392854639 date "2009-01-01" @default.
- W2392854639 modified "2023-09-28" @default.
- W2392854639 title "Effect of vinpocetine on lipid peroxidation of human umbilical vein endothelial cell in vitro induced by reactive oxygen species" @default.
- W2392854639 hasPublicationYear "2009" @default.
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