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- W2392857137 abstract "The Zn2+ modulatory effect on inward rectifying potassium channel(Kir) was examined using whole-cell patch clamp technique.The main results of the present study are: 1) Zn2+ at millimolar concentration has inhibitory effect on Kir currents when extracellular pH is 6.8,but micromolar concentration of Zn2+ has no effect;2) Zn2+ has no effect on Kir currents when extracellular pH is in physiological rang(pH=7.2).These results suggest that the modulatory effect of Zn2+ on Kir currents is related to extracellular pH.Such Zn2+ inhibitory effect on Kir currents may contribute to protect the neurons from apoptosis in condition of hypoxia/ischemia." @default.
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- W2392857137 date "2011-01-01" @default.
- W2392857137 modified "2023-09-24" @default.
- W2392857137 title "Modulation of Extracellular Zn(2+)on Inward-Rectifying Potassium Channel Expressed on H1 Type Horizontal Cell in Carp Retina" @default.
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