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- W2392873470 abstract "Objective To observe the effects of abdominal lavage fluid from rats with radiation injury,burn injury and combined radiation|burn injury on growth of hematopoietic progenitor cells. Methods Rats were irradiated with 12 Gy whole body 60 Co γ rays and/or inflicted with 30% TBSA III degree burn with a 5 kW bromotungsten lamp.The abdominal lavage fluid from the animals was collected at 3 h,12 h,24 h,48 h,72 h after injury, separately. Then each of the lavage fluid samples was added to the medium of cultured erythrocyte progenitor cells (CFU|E,BFU|E) or of cultured granulocyte|macrophage progenitor cells (CFU|GM) at a final concentration of 40 μg/ml. Results The colony numbers of CFU|E,BFU|E and CFU|GM formed after addition of the lavage fluid from rats with burn injury or combined radiation|burn injury were significantly higher than those from normal rats at 3 h,12 h,24 h,48 h and 72 h after injury and reached their peak values at 24 h after injury (215 7%,202 3% and 241 2%,respectively from solely burned rats;188 1%,147 7% and 204 6%,respectively from rats with combined radiation|burn injury as compared with that of normal rats).However,only few CFU|E,BFU|E or CFU|GM colonies were found after addition of the lavage fluid from solely irradiated rats. Conclusions The abdominal lavage fluid from rats with sole burn injury or combined radiation|burn injury promotes growth of erythrocyte and granulocyte progenitor cells.On the contrary,the lavage fluid from solely irradiated rats shows inhibiting effects.;" @default.
- W2392873470 created "2016-06-24" @default.
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- W2392873470 date "2003-01-01" @default.
- W2392873470 modified "2023-09-23" @default.
- W2392873470 title "Effects of abdominal lavage fluid from rats with radiation injury and combined radiation-burn injury on growth of hematopoietic progenitor cells" @default.
- W2392873470 hasPublicationYear "2003" @default.
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