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- W2392901089 abstract "Objective:To explore the clinical therapeutic effectiveness of trimetazidine on the treatment of dilated cardiomyopathy( DCM) associated with chronic congestive heart failure(CHF). Methods:100 patients with DCM associated with CHF were randomly divided into control group and observation group. Patients in the control group were given routinely treated. Patients in the observation group were treated with trimetazidine on the basis of the routine treatment. The course of treatment lasted 24 weeks. The grade of cardiac function, left ventricular ejection fraction(LVEF),left ventricular end diastolic diameter (LVEDD) and cardiac output (CO)were determined before and after 24 weeks after treatment in both groups. Results:After 24 weeks of treatment, the total effective rate in the control group was 72.00% (36/50), and in the observation group was 88.00% (44/50), the difference was statistically significant(P0.05);Both groups the level of LVEDD, CO, LVEF were significantly improved compared with before the treatment(P0.01), and the index in the observation group were better than the control group(P0.01 or P0.05). Conclusion:For patients with dilated cardiomyopathy, long-time treatment with trimetazidine in combination with routine therapy can significantly improve the left cardiac function." @default.
- W2392901089 created "2016-06-24" @default.
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- W2392901089 date "2011-01-01" @default.
- W2392901089 modified "2023-09-27" @default.
- W2392901089 title "Clinical therapeutic effectiveness of trimetazidine on the treatment of patients with dilated cardiomyopathy associated with chronic congestive heart failure" @default.
- W2392901089 hasPublicationYear "2011" @default.
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