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- W2392919571 abstract "Objective:To study the effects of antihypertensives in the changes of concentration of GMP140 and vWF in plasma of essential hypertension(EH) patients.Methods:Radioimmunoassay was used to measure plasma GMP140 and ELISA was used to measure vWF in 30 patients with EH before and after antihypertensive treatment for 6 weeks.Serum levels of GMP140 and vWF were compared with those in 30 healthy subjects.Results:The concentration of plasma GMP140 and vWF and Hct% in EH group were significantly higher than that in control group which also significantly lowered after 6 weeks treatment with ACEI and CCB.There was significant correlation between systolic or diastolic pressure with GMP140 and vWF or Hct%,while no correlation with the other counting characteristics.Conclusion:PTS in EH is relevant to activiation of platelets and the combining treatment of ACEI and CCB can decrease the activiation of platelets and release prothrombotic state(PTS) in patients with EH." @default.
- W2392919571 created "2016-06-24" @default.
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- W2392919571 date "2008-01-01" @default.
- W2392919571 modified "2023-09-23" @default.
- W2392919571 title "The Effects of Antihypertensives in the Changes of the Concentration of Plasma GMP140 and vWF in Patients with Elementary Hypertension" @default.
- W2392919571 hasPublicationYear "2008" @default.
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