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- W2392945018 abstract "Hydrophilic matrix tablets of nifedipine(NFP)were prepared,together with the examination of the influences of formulation and preparation parameters on the drug release profiles.The optimal formulation obtained was:nifedipine solid dispersion 〔m(NFP)∶m(HPMC)=1∶1〕 60 mg,PEO 20 mg and mannitol 10 mg.The mixture was compressed directly and the hardness of the tablet was(85±10)N.The cumulative release rate within 14h was 89.69%.Linear relationship between the accumulated release data and the time is 0.996 2.It shows an excellent zero-order release profile in vitro for 14 h." @default.
- W2392945018 created "2016-06-24" @default.
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- W2392945018 date "2007-01-01" @default.
- W2392945018 modified "2023-09-23" @default.
- W2392945018 title "Preparation and in vitro Release Property of Nifedipine Matrix Tablet" @default.
- W2392945018 hasPublicationYear "2007" @default.
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