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- W2392948640 abstract "Objective To explore the association of serum vaspin level with the T2DM macrovascular complications.Methods Sixty-five newly diagnosed T2DM patients were divided into simple T2DM group(SDM group,n=33),and T2DM macrovascular complication group(MV group,n=32).Thirty healthy people with normal glucose tolerance were selected as the controls(NC group).Serum vaspin was measured by ELISA method.FPG,2 hPG,FIns,HbA1c,hsC-RP,and lipid profiles were measured as well.BMI and waist-to-hip ratio(WHR) were recorded and insulin sensitivity was assessed by HOMA model.Results The serum vaspin levels of three groups were in order of MV group(0.46±0.24) NC group(0.49±0.21) SDM group(0.67±0.39).In the SDM group,the vaspin level was positively correlated with sex,BMI,FIns,TG,HOMA-IR,hsC-RP,and WHR(r=0.561,0.653,0.632,0.578,0.516,0.698,0.625,P0.05 or P0.01),and negatively correlated with HDL-C(r=-0.647,P0.01).In the MV group,the vaspin level was negatively correlated with SBP,HOMA-IR,and hsC-RP(r=-0.592,-0.526,-0.628,P0.05 or P0.01),and positively with sex(r=0532,P0.05).Logistic regression analysis showed that TG,BMI,and the fasting serum vaspin levels were the main risk factors for macrovascular complications in T2DM.Conclusion Vaspin plays a very important role in type 2 diabetes mellitus with macrovascular complications." @default.
- W2392948640 created "2016-06-24" @default.
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- W2392948640 date "2012-01-01" @default.
- W2392948640 modified "2023-09-26" @default.
- W2392948640 title "Association between serum vaspin level and the T2DM macrovascular complications" @default.
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