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- W2392952313 abstract "Objective To evaluate the effects of expiratory trigger sensitivity(ETS) on respiratory mechanics in chronic obstructive pulmonary disease(COPD) patients during pressure support ventilation(PSV).Methods Thirty-one patients with acute exacerbation of COPD complicating respiratory failure(RF) were enrolled in the study.The patients were admitted into respiratory intensive care unit(RICU) from December,2006 to January,2008 for invasive mechanical ventilation,who were applied with Galileo Gold breathing machine connected by tracheal intubation or incision of trachea.After patient conditions were stable,PSV mode was used.Three levels of ETS,5%,35%,and 65% of peak inspiratory flow(PIF) were studied in random order with the other parameters unchanged.Each ETS level lasted 30 to 60 minutes and respiratory mechanics and hemodynamics were recorded and compared.Self-control comparison study was measured.Results With ETS% level increasing,Vt,Ti,I∶E,Exp Flow reduced(P0.01),and the different ETS% of Vt was(553.20±89.90) ml,(499.18±63.68) ml,(450.40±59.99) ml(P0.01),the different ETS% of Ti was(1.18±0.34) s,(0.88±0.21) s,(0.65±0.12) s(P0.01),the different ETS% of I∶E was 0.55±0.13,0.45±0.09,0.33±0.06(P0.01),the different ETS% of Exp flow was(52.49±7.95) L/min,(39.64±6.85) L/min,(26.28±12.55) L/min(P0.01);rapid shallow breathing(RSB),Rexp increased(P0.01),the different ETS% of RSB was 34.81±10.14,44.37±10.85,52.81±12.53(P0.01),the different ETS% of Rexp was(15.15±3.73) cm H2O·L-1·s-1,(19.96±3.85) cm H2O·L-1·s-1,(35.38±13.75) cm H2O·L-1·s-1(P0.01).With ETS% level increasing,there were no significant differences in VE and Te(P0.05).With ETS% level increasing,Insp flow increased,Rinsp reduced,there were no significant differences in different ETS%(P0.05).With ETS% level increasing,HR increased,there were no significant differences in different ETS%(P0.05).With ETS% level increasing,SpO2 reduced,there was only significant difference between ETS 5% and ETS 65%(P0.05).Bpsys,Bpdia,MAP were lower in the level of ETS 35%,but there were no significant differences in different ETS%(P0.05).Conclusion There are different effects of different ETS% on respiratory mechanics in COPD patients during PSV." @default.
- W2392952313 created "2016-06-24" @default.
- W2392952313 creator A5040110606 @default.
- W2392952313 date "2009-01-01" @default.
- W2392952313 modified "2023-09-23" @default.
- W2392952313 title "Effects of expiratory trigger sensitivity on respiratory mechanics in chornic obstructive pulmonary disease patients during pressure support ventilation" @default.
- W2392952313 hasPublicationYear "2009" @default.
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