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- W2392992908 abstract "Objective To investigate the infection of transfusion transmitted virus(TTV) in maintenance hemodialysis patients and analyse a part of TTV DNA sequence. Method Denome DNA of TTV ORF1 was amplified in sera from 80 hemodialysis patients and 12 nurses of dialysis center using a nested polymerase chain reaction(PCR) assay with specific primers. After molecular cloning and sequencing of the PCR products, the genetic valuations of the TTV DNA were analyzed. Results 35 % (28/80)of hemodialysis patients and Eight. 3% (1/12) of dialysis operators were TTV DNA postitive. Compared with the reported Japanese isolate, the mucleotide sequence homologies of TFV isolates in this experiment was 96.7%. 8 patients had HBV and TTV infection, 5 patients HCV and TTV infection, while 2 patients had HBV, HCV and TTV infection. 57% of the TTV DNA positive patients had the transfusion history. Conclusions TTV infection is seriously in hemodialysis patients, of whom most have transfusion history, and can be found in dialysis operators. TTV can be co-infected with HBV and HCV. The infection of TTV without transfusion should be considered as well." @default.
- W2392992908 created "2016-06-24" @default.
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- W2392992908 date "2000-01-01" @default.
- W2392992908 modified "2023-09-23" @default.
- W2392992908 title "Transfusion transmitted virus infection and its genetic analysis in maintenance hemodialysis patients" @default.
- W2392992908 hasPublicationYear "2000" @default.
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