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- W2393015819 abstract "[Objective]To study the vacuolating cytotoxin gene A(vacA) subtype of Helicobacter pylori(Hp) distributed in Hubei area,and to explore the association between different vacA subtypes and chronic gastritis(CG) and chronic peptic ulcer(CPU).[Methods]The shared-primer PCR technique and specific PCR primers were used in our research to subtype the vacA gene of Hp strains isolated from gastric mucosal biopsies of 74 cases and the association between the vacA sub-genotypes and their clinical outcomes was evaluated by SAS statistical soft ware.[Results]It was primarily s1a-m2 in Hubei area and the dominant vacA subtypes of prevalent strains in Hubei area that were similar to those in Shanghai and Guangzhou area.In addition to s1a-m2,there were other subtypes like s1a-m1,s1b-m1,s1b-m2,s1c-m1 and s1c-m2.Furthermore,8 strains of all could not be subtyped.[Conclusion]There is no correlation between different genotype of vacA and distinct clinical outcomes in Hubei area,the further investigation and research are still needed." @default.
- W2393015819 created "2016-06-24" @default.
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- W2393015819 date "2006-01-01" @default.
- W2393015819 modified "2023-09-25" @default.
- W2393015819 title "Genotyping of vacA in helicobacter pylori and the association of vacA genotypes with their clinical outcomes in Hubei area" @default.
- W2393015819 hasPublicationYear "2006" @default.
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