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- W2393044488 abstract "Objective To study the property of the IP 3 sensitive and non IP 3 sensitive calcium stores in rat astrocytes and their relationship. Methods By using the microfluorescent technique, the intracellular calcium signals of the astrocytes were detected and observed dynamically. By different combination of calcium store activators (MCh, CAF) and a decoupling agent (FCCP), the astrocytes were stimulated and its effects on the intracellular calcium signals were analysed. Results In most cells, when one kind of calcium store was attenuated or exhausted, the magnitude of elevation of [Ca 2+ ] I , induced by the calcium store activator, was not significantly affected or only slightly inhibited; but in some cells, this magnitude of elevation of [Ca 2+ ] I was markedly reduced. Conclusion There are two types of calcium stores existing in the astrocytic endoplasmic reticulum, one is IP 3 sensitive and the other is non IP 3 sensitive. They have intimate or relatively independent relationship." @default.
- W2393044488 created "2016-06-24" @default.
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- W2393044488 date "2002-01-01" @default.
- W2393044488 modified "2023-09-25" @default.
- W2393044488 title "Property of IP_3-sensitive and non-IP_3- sensitive calcium stores in rat astrocytes and their relationship" @default.
- W2393044488 hasPublicationYear "2002" @default.
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