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- W2393048014 abstract "Objective To explore the effect of etomidate on the percentages ofδ-band and β2-band of quantitative pharmaco-electroencephalogram(QPEEG)in rabbits.Methods Thirty healthy adult rabbits were equally randomized into 5groups of I(intravenously injected fat emulsion 1ml/kg), LD,MD,HD(intravenously injected etomidate 0.25,0.50,1.00 mg/kg,respectively)and NS(intravenous injection of normal saline as the control).The percentages ofδ-band andβ2-band power in the frontal,parietal,occipital and temporal area of the left and right brain in rabbits were noted down by QPEEG at 30seconds before administration and 30seconds,1,2,3,5and 10minutes after administration,respectively.QPEEG activity was processed with power spectual analysis in order to analyze the changes ofδ-band andβ2-band power percentage.Results Compared with before,there was no significant difference inδ-band andβ2-band power percentage in all brain regions in groups of I and NS after administration(P0.05).The percentage ofδ-band power was increased and that ofβ2-band power was decreased in all brain regions in groups of LD(P0.05or P0.05),MD and HD(P0.05or P0.01)after administration,and the changes ofδ-band andβ2-band power were correlated with the dose of etomidate.Conclusion Etomidate is able to increase the percentage of δ-band and decrease the percentage ofβ2-band power in QPEEG of rabbits in a dose-dependent manner.The percentages ofδ-band andβ2-band power may become monitoring indicators for evaluating the depth of etomidate anesthesia." @default.
- W2393048014 created "2016-06-24" @default.
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- W2393048014 date "2014-01-01" @default.
- W2393048014 modified "2023-09-22" @default.
- W2393048014 title "Effect of etomidate onδ-band and β_2-band power of quantitative pharmaco-electroencephalography in rabbits" @default.
- W2393048014 hasPublicationYear "2014" @default.
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